A case of Graves' ophthalmopathy associated with pembrolizumab (Keytruda) therapy

Date Published:

2018 Apr 04


We present the first reported case of Graves' orbitopathy induced by pembrolizumab, a new FDA-approved drug used for the treatment of multiple refractory solid tumors and classic Hodgkin lymphoma. Pembrolizumab elicits T-lymphocyte proliferation; we suspect that thyroid eye disease may result in some cases.

Last updated on 05/07/2018