@article {1195241,
	title = {Long-term impact of endoscopic orbital decompression on sinonasal-specific quality of life},
	journal = {Laryngoscope},
	volume = {128},
	number = {4},
	year = {2018},
	month = {2018 Apr},
	pages = {785-788},
	abstract = {OBJECTIVE: Endoscopic orbital decompression (EOD) is the workhorse surgical intervention for severe thyroid eye disease in Graves disease. Although EOD is a safe and effective procedure, the objective of this study is to determine the impact of orbital decompression on long-term sinonasal-pecific quality of life.

METHODS: Retrospective study of 27 patients who underwent EOD by a single surgeon. The primary endpoint was change in preoperative 22-item Sinonasal Outcomes Test (SNOT-22) score at a minimum of 1 year. The secondary endpoint was to determine whether the performance of septoplasty for surgical access in patients without nasal obstruction impacted domain 1 (i.e., rhinologic domain) and total SNOT-22 scores.

RESULTS: The mean follow-up was 25.7 {\textpm} 11.4 months. Domain 1 scores significantly increased at the first postoperative visit (P <= 0.01) and returned to baseline values between 1 and 3 months. At 1 year, significant improvements in both total score and domain 4 and 5 (psychological and sleep dysfunction, respectively) scores were seen (P < 0.01 for all scores). Septoplasty was not associated with a significant change in SNOT-22 score at 1 year (P = 0.48).

CONCLUSION: Endoscopic orbital decompression is associated at 1 year with a significant improvement in sinonasal-specific quality of life, which is driven by the psychological and sleep dysfunction domains. Adjunctive septoplasty has no significant impact on SNOT-22 scores.

LEVEL OF EVIDENCE: 4. Laryngoscope, 128:785-788, 2018.},
	issn = {1531-4995},
	doi = {10.1002/lary.26812},
	author = {Mueller, Sarina K and Miyake, Marcel M and Lefebvre, Daniel R and Freitag, Suzanne K and Bleier, Benjamin S}
}
