@article {1295865,
	title = {The Challenge of Pediatric Uveitis: Tertiary Referral Center Experience in the United States},
	journal = {Ocul Immunol Inflamm},
	year = {2018},
	month = {2018 Jan 15},
	pages = {1-8},
	abstract = {PURPOSE: To describe the distribution, clinical findings, visual outcomes, treatment, and complications of children with uveitis at a tertiary referral ophthalmic center. METHODS: Retrospective cohort study. We reviewed the medical records of all patients <=16\&nbsp;years with uveitis referred to Massachusetts Eye Research and Surgery Institution from March 2005 to July 2016. RESULTS: Of 286 included children, 62.24\% were female. Mean age of onset was 8.4\&nbsp;years. The uveitis was mainly anterior (61.9\%), recurrent (68.53\%), bilateral (81.82\%), and noninfectious (96.5\%). Idiopathic cases accounted for 51.4\%. The most frequent systemic association was juvenile idiopathic arthritis (34.96\%). The majority of patients (78.32\%) experienced complications. All patients, except one, needed systemic therapy. CONCLUSION: Pediatric uveitis is challenging to diagnose and manage, with frequent and potentially severe complications. Most cases were bilateral, recurrent, and idiopathic. Prompt referral to uveitis-specialized centers and an appropriate systemic therapy are mandatory for good visual outcomes.},
	issn = {1744-5078},
	doi = {10.1080/09273948.2017.1420202},
	author = {Ferrara, Mariantonia and Eggenschwiler, Laura and Stephenson, Andrew and Montieth, Alyssa and Nakhoul, Nakhoul and Ara{\`u}jo-Miranda, Rafael and Foster, C Stephen}
}
