@article {1302173,
	title = {Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma},
	journal = {Hum Mol Genet},
	volume = {27},
	number = {8},
	year = {2018},
	month = {2018 Apr 15},
	pages = {1486-1496},
	abstract = {Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 loci have been associated with POAG in Asians. We carried out a genome-wide association study and a replication study that included a total of 7378 POAG cases and 36~385 controls from a Japanese population. After combining the genome-wide association study and the two replication sets, we identified 11 POAG-associated loci, including 4 known (CDKN2B-AS1, ABCA1, SIX6 and AFAP1) and 7 novel loci (FNDC3B, ANKRD55-MAP3K1, LMX1B, LHPP, HMGA2, MEIS2 and LOXL1) at a genome-wide significance level (P ,
	issn = {1460-2083},
	doi = {10.1093/hmg/ddy053},
	author = {Shiga, Yukihiro and Akiyama, Masato and Nishiguchi, Koji M and Sato, Kota and Shimozawa, Nobuhiro and Takahashi, Atsushi and Momozawa, Yukihide and Hirata, Makoto and Matsuda, Koichi and Yamaji, Taiki and Iwasaki, Motoki and Tsugane, Shoichiro and Oze, Isao and Mikami, Haruo and Naito, Mariko and Wakai, Kenji and Yoshikawa, Munemitsu and Miyake, Masahiro and Yamashiro, Kenji and Kashiwagi, Kenji and Iwata, Takeshi and Mabuchi, Fumihiko and Takamoto, Mitsuko and Ozaki, Mineo and Kawase, Kazuhide and Aihara, Makoto and Araie, Makoto and Yamamoto, Tetsuya and Kiuchi, Yoshiaki and Nakamura, Makoto and Ikeda, Yasuhiro and Sonoda, Koh-Hei and Ishibashi, Tatsuro and Nitta, Koji and Iwase, Aiko and Shirato, Shiroaki and Oka, Yoshitaka and Satoh, Mamoru and Sasaki, Makoto and Fuse, Nobuo and Suzuki, Yoichi and Cheng, Ching-Yu and Khor, Chiea Chuen and Baskaran, Mani and Perera, Shamira and Aung, Tin and Vithana, Eranga N and Cooke Bailey, Jessica N and Kang, Jae H and Pasquale, Louis R and Haines, Jonathan L and Wiggs, Janey L and Burdon, Kathryn P and Gharahkhani, Puya and Hewitt, Alex W and Mackey, David A and Macgregor, Stuart and Craig, Jamie E and Allingham, R Rand and Hauser, Micheal and Ashaye, Adeyinka and Budenz, Donald L and Akafo, Stephan and Williams, Susan E I and Kamatani, Yoichiro and Nakazawa, Toru and Kubo, Michiaki}
}
