@article {1304381,
	title = {SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN COATS DISEASE},
	journal = {Retina},
	volume = {39},
	number = {6},
	year = {2019},
	month = {2019 Jun},
	pages = {1177-1185},
	abstract = {PURPOSE: To evaluate microstructural retinal abnormalities on spectral domain optical coherence tomography (SD-OCT) imaging of eyes with Coats disease. METHODS: This is a multicenter, retrospective study in which SD-OCT images of patients with treatment-naive Coats disease were correlated with clinical examination and visual acuity and, when available, followed longitudinally over time. RESULTS: Macular SD-OCT of 27 eyes with Coats disease revealed intraretinal edema (59\%), intraretinal exudates (67\%), subretinal fluid (37\%), subretinal exudate (48\%), ellipsoid zone disruption (52\%), external limiting membrane disruption (41\%), and subfoveal nodule (26\%). All these microstructural abnormalities correlated with worse baseline and final visual acuities (P \&lt; 0.05) on univariate analysis, except for intraretinal edema which exhibited a nonstatistically significant trend toward worse baseline visual acuity (P = 0.16). Within stage 2b eyes, external limiting membrane disruption and subretinal nodule on SD-OCT were associated with worse baseline visual acuity (P = 0.02 for both), and there was a trend toward worse final visual acuity with external limiting membrane disruption and subretinal nodule (P = 0.17 for both) and worse baseline (P = 0.08) and final (P = 0.13) visual acuities with ellipsoid zone disruption. No microstructural abnormalities were noted on OCT of fellow eyes. CONCLUSION: Spectral domain OCT can identify microstructural abnormalities in Coats disease that are associated on univariate analysis with worse baseline visual acuity and visual prognosis. Further larger studies are necessary.},
	issn = {1539-2864},
	doi = {10.1097/IAE.0000000000002120},
	author = {Gupta, Mrinali P and Dow, Eliot and Jeng-Miller, Karen W and Mukai, Shizuo and Orlin, Anton and Xu, Kunyong and Yonekawa, Yoshihiro and Chan, R V Paul}
}
