@article {1351127,
	title = {Treatment of pseudodendrites in herpes zoster ophthalmicus with topical ganciclovir 0.15\% gel},
	journal = {Cornea},
	volume = {33},
	number = {2},
	year = {2014},
	month = {2014 Feb},
	pages = {109-13},
	abstract = {PURPOSE: There is no standard of treatment for epithelial pseudodendrites in herpes zoster ophthalmicus (HZO). The purpose of this study is to report the topical antiviral drug, 0.15\% ganciclovir for treatment of these lesions. METHODS: This is a retrospective, interventional case series of 4 patients who were diagnosed with HZO epithelial pseudodendrites despite being given oral antiviral treatment and who underwent 0.15\% ganciclovir gel topical treatment. Main outcome measures included epithelial healing time, visual acuity, and corneal sensation. RESULTS: All 4 patients were immunocompetent and had epithelial lesions unresponsive to antiviral treatment with oral valacyclovir. Treatment with topical 0.15\% ganciclovir gel 5 times a day resulted in the lesions healing successfully within 7 days with improved visual acuity in 3 patients and an increase in corneal sensation in 2 of the 4 patients. CONCLUSIONS: Topical 0.15\% ganciclovir gel, 5 times a day until pseudodendritic lesion healing and tapering to bid for 2 to 4 weeks thereafter, is an effective treatment for pseudodendrites in HZO-affected cases that are often a challenge to manage with other oral or topical antivirals.},
	keywords = {Administration, Topical, Aged, Antiviral Agents, Female, Ganciclovir, Herpes Zoster Ophthalmicus, Humans, Keratitis, Dendritic, Male, Middle Aged, Ophthalmic Solutions, Retrospective Studies, Treatment Outcome, Visual Acuity},
	issn = {1536-4798},
	doi = {10.1097/ICO.0000000000000020},
	author = {Aggarwal, Shruti and Cavalcanti, Bernardo M and Pavan-Langston, Deborah}
}
