@article {1351182,
	title = {Influence of diabetes and diabetes type on anatomic and visual outcomes following central rein vein occlusion},
	journal = {Eye (Lond)},
	volume = {28},
	number = {3},
	year = {2014},
	month = {2014 Mar},
	pages = {259-68},
	abstract = {PURPOSE: To determine the influence of diabetes and diabetes type on ocular outcomes following central retinal vein occlusion (CRVO). METHODS: Retrospective chart review of all patients evaluated over a 4-year period in a tertiary diabetes eye care center. Ophthalmic findings were recorded including visual acuity and the presence of retinal neovascularization at presentation, after 3-6 months, and at last follow-up. RESULTS: The records of 19,648 patients (13,571 diabetic; 6077 nondiabetic) were reviewed. The prevalence of CRVO in diabetic patients (N=72) and nondiabetic patients (N=27) were 0.5 and 0.4\%, respectively. Disc neovascularization (21.3 vs 0.0\%, P=0.05) and panretinal photocoagulation (PRP) (48.7 vs 21.4\%, P=0.01) were more common in diabetic patients compared with nondiabetic patients. Compared with type 2 diabetic patients, retinal neovascularization (28.6 vs 3.7\%, P=0.004) and subsequent PRP (78.6 vs 41.9\%, P=0.01) were more likely in type 1 patients. Optic nerve head collateral vessels (CVs) were observed less than half as often (21.4 vs 56.5\%, P=0.04) in patients with type 1 diabetes. Presence of optic nerve head CVs at baseline was associated with less likelihood of PRP (14.3 vs 46.1\%, P=0.03). CONCLUSIONS: In this cohort, the rates of CRVO in diabetic and nondiabetic patients were similar to previously published population-based studies. Following CRVO, diabetic patients had higher rates of disc neovascularization and were more likely to require subsequent PRP than nondiabetic patients. As compared with CRVO patients with type 2 diabetes, patients with type 1 diabetes and CRVO had worse anatomic outcomes with substantially increased risks of retinal neovascularization and PRP; however, final visual acuity outcomes were similar.},
	keywords = {Adult, Aged, Aged, 80 and over, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Retinopathy, Female, Fluorescein Angiography, Glaucoma, Open-Angle, Humans, Intraocular Pressure, Laser Coagulation, Male, Middle Aged, Retinal Neovascularization, Retinal Vein Occlusion, Retrospective Studies, Risk Factors, Visual Acuity},
	issn = {1476-5454},
	doi = {10.1038/eye.2014.1},
	author = {Santiago, J G and Walia, S and Sun, J K and Cavallerano, J D and Haddad, Z A and Aiello, L P and Silva, P S}
}
