@article {1363215,
	title = {Predictability of intraocular lens power calculation formulae in infantile eyes with unilateral congenital cataract: results from the Infant Aphakia Treatment Study},
	journal = {Am J Ophthalmol},
	volume = {156},
	number = {6},
	year = {2013},
	month = {2013 Dec},
	pages = {1252-1260.e2},
	abstract = {PURPOSE: To compare accuracy of intraocular lens (IOL) power calculation formulae in infantile eyes with primary IOL implantation. DESIGN: Comparative case series. METHODS: The Hoffer Q, Holladay 1, Holladay 2, Sanders-Retzlaff-Kraff (SRK) II, and Sanders-Retzlaff-Kraff theoretic (SRK/T) formulae were used to calculate predicted postoperative refraction for eyes that received primary IOL implantation in the Infant Aphakia Treatment Study. The protocol targeted postoperative hyperopia of\&nbsp;+6.0 or\&nbsp;+8.0 diopters (D). Eyes were excluded for invalid biometry, lack of refractive data at the specified postoperative visit, diagnosis of glaucoma or suspected glaucoma, or sulcus IOL placement. Actual refraction 1\&nbsp;month after surgery was converted to spherical equivalent and prediction error (predicted refraction\&nbsp;- actual refraction) was calculated. Baseline characteristics were analyzed for effect on prediction error for each formula. The main outcome measure was absolute prediction error. RESULTS: Forty-three eyes were studied; mean axial length was 18.1 {\textpm} 1.1\&nbsp;mm (in 23 eyes, it was \&lt;18.0\&nbsp;mm). Average age at surgery was 2.5 {\textpm} 1.5\&nbsp;months. Holladay 1 showed the lowest median absolute prediction error (1.2 D); a paired comparison of medians showed clinically similar results using the Holladay 1 and SRK/T formulae (median difference, 0.3 D). Comparison of the mean absolute prediction error showed the lowest values using the SRK/T formula (1.4 {\textpm} 1.1 D), followed by the Holladay 1 formula (1.7 {\textpm} 1.3 D). Calculations with an optimized constant showed the lowest values and no significant difference between the Holladay 1 and SRK/T formulae (median difference, 0.3 D). Eyes with globe AL of less than 18\&nbsp;mm had the largest mean and median prediction error and absolute prediction error, regardless of the formula used. CONCLUSIONS: The Holladay 1 and SRK/T formulae gave equally good results and had the best predictive value for infant eyes.},
	keywords = {Aphakia, Postcataract, Biometry, Cataract, Cataract Extraction, Humans, Infant, Lens Implantation, Intraocular, Lenses, Intraocular, Optics and Photonics, Refraction, Ocular, Reproducibility of Results, Treatment Outcome, Visual Acuity},
	issn = {1879-1891},
	doi = {10.1016/j.ajo.2013.07.014},
	author = {VanderVeen, Deborah K and Trivedi, Rupal H and Nizam, Azhar and Lynn, Michael J and Lambert, Scott R and Infant Aphakia Treatment Study Group}
}
