@article {1363260,
	title = {Wound anatomy after type 1 Boston KPro using oversized back plates},
	journal = {Cornea},
	volume = {32},
	number = {12},
	year = {2013},
	month = {2013 Dec},
	pages = {1531-6},
	abstract = {PURPOSE: To compare the anatomy of the graft-host junction and anterior chamber angle after Boston Keratoprosthesis (KPro) placement using oversized (9.5-mm) and standard (8.5-mm) back plates. METHODS: Six patients with 9.5-mm titanium back plates and 10 patients with 8.5-mm titanium back plates were imaged by anterior segment optical coherence tomography 6 to 12 months after KPro placement. The location of the graft-host junction in relation to the back plate, the corneal thickness at the graft-host junction, and the anterior chamber angle were assessed. The clinical outcomes and incidence of retroprosthetic membrane (RPM) formation in this cohort were retrospectively evaluated. RESULTS: The oversized back plates completely covered the graft-host junction in all quadrants, allowing the complete apposition of the posterior surface of the carrier graft with the host cornea, with decreased graft-host junction wound thickness. The standard back plates covered the posterior aspect of the carrier graft but not the graft-host junction or the host cornea, resulting in a significantly thicker graft-host junction. None of the patients with larger back plates developed a significant RPM during a 12-month follow-up period. One patient with a larger back plate developed a corneal melt at the KPro stem as a result of chronic exposure. CONCLUSIONS: Oversized KPro back plates effectively cover the graft-host junction without any adverse effects on angle anatomy or wound healing. This may be a strategy to provide better wound apposition, reduce RPM formation, and reduce angle closure from iris synechiae to the wound.},
	keywords = {Adult, Aged, Anterior Eye Segment, Artificial Organs, Cornea, Corneal Diseases, Female, Humans, Male, Middle Aged, Prosthesis Implantation, Retrospective Studies, Titanium, Tomography, Optical Coherence, Wound Healing},
	issn = {1536-4798},
	doi = {10.1097/ICO.0b013e3182a854ac},
	author = {Cruzat, Andrea and Shukla, Anita and Dohlman, Claes H and Colby, Kathryn}
}
