@article {1430520, title = {Outcomes of Unilateral Cataracts in Infants and Toddlers 7 to 24 Months of Age: Toddler Aphakia and Pseudophakia Study (TAPS)}, journal = {Ophthalmology}, volume = {126}, number = {8}, year = {2019}, month = {2019 Aug}, pages = {1189-1195}, abstract = {PURPOSE: To evaluate outcomes of unilateral cataract surgery in children 7 to 24 months of age. DESIGN: Retrospective case series at 10 Infant Aphakia Treatment Study (IATS) sites. PARTICIPANTS: The Toddler Aphakia and Pseudophakia Study is a registry of children treated by surgeons who participated in the IATS. METHODS: Children underwent unilateral cataract surgery with or without intraocular lens (IOL) placement during the IATS enrollment years of 2004 and\ 2010. MAIN OUTCOME MEASURES: Intraoperative complications, adverse events (AEs), visual acuity, and strabismus. RESULTS: Fifty-six children were included with a mean postoperative follow-up of 47.6 months. Median age at cataract surgery was 13.9 months (range, 7.2-22.9). Ninety-two percent received a primary IOL. Intraoperative complications occurred in 4 patients (7\%). At 5 years of age, visual acuity of treated eyes was very good (>=20/40) in 11\% and poor (<=20/200) in 44\%. Adverse events were identified in 24\%, with a 4\% incidence of glaucoma suspect. An additional unplanned intraocular surgery occurred in 14\% of children. Neither AEs nor intraocular reoperations were more common for children with surgery at 7 to 12 months of age than for those who underwent surgery at 13 to 24 months of age (AE rate, 21\% vs. 25\% [P\ = 0.60]; reoperation rate, 13\% vs. 16\% [P\ = 1.00]). CONCLUSIONS: Although most children underwent IOL implantation concurrent with unilateral cataract removal, the incidence of complications, reoperations, and glaucoma was low when surgery was performed between 7 and 24 months of age and compared favorably with same-site IATS data for infants undergoing surgery before 7 months of age. Our study showed that IOL implantation is relatively safe in children older than 6\ months and younger than 2 years.}, issn = {1549-4713}, doi = {10.1016/j.ophtha.2019.03.011}, author = {Bothun, Erick D and Wilson, M Edward and Traboulsi, Elias I and Diehl, Nancy N and Plager, David A and VanderVeen, Deborah K and Freedman, Sharon F and Yen, Kimberly G and Weil, Natalie C and Loh, Allison R and Morrison, David and Anderson, Jill S and Lambert, Scott R and Toddler Aphakia and Pseudophakia Study Group (TAPS)} }