@article {1460368,
	title = {ETIOLOGY AND CLINICAL CHARACTERISTICS OF MACULAR EDEMA IN PATIENTS WITH FAMILIAL EXUDATIVE VITREORETINOPATHY},
	journal = {Retina},
	volume = {40},
	number = {7},
	year = {2020},
	month = {2020 Jul},
	pages = {1367-1373},
	abstract = {PURPOSE: To describe the etiology and clinical characteristics of macular edema (ME) in patients with familial exudative vitreoretinopathy. METHODS: Observational, retrospective case series of 30 patients (34 eyes) with ME and familial exudative vitreoretinopathy who underwent spectral-domain optical coherence tomography imaging between 2009 and 2016. Baseline and follow-up optical coherence tomographies were correlated with color fundus photography and fluorescein angiography. RESULTS: The average age was 20.6 years (6.6-68.7). Eighteen eyes exhibited cystoid ME (52.9\%), 14 noncystoid ME (41.2\%), and 2 eyes (5.9\%) with both. Macular edema was foveal in 52.9\% (n = 18). Eighteen of 24 eyes (64.3\%) with an available fluorescein angiography showed leakage from ME. The most common structural feature was posterior hyaloidal organization/contraction (n = 15). Sixteen eyes were treated with topical or intravitreal steroids (n = 6), intravitreal anti-vascular endothelial growth factor (n = 3), or pars plana vitrectomy with membrane stripping (n = 7). There was no difference between mean preoperative and postoperative LogMAR visual acuity (0.63 [20/85] vs. 0.87 [20/148], P = 0.35) after vitrectomy despite a statistical improvement in the mean central foveal thickness (596 mm vs. 303 mm, P = 0.04). CONCLUSION: Macular edema in familial exudative vitreoretinopathy occurs most commonly because of traction. Vitrectomy is effective for relieving tractional forces with anatomical improvement.},
	issn = {1539-2864},
	doi = {10.1097/IAE.0000000000002623},
	author = {Rao, Prethy and Lertjirachai, Itsara and Yonekawa, Yoshihiro and Hasbrook, Madeline and Thomas, Benjamin J and Wood, Edward H and Mehta, Neesurg and Mane, Greta and Drenser, Kimberly A and Trese, Michael T and Capone, Antonio}
}
