@article {1470981,
	title = {Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography},
	journal = {J Glaucoma},
	volume = {28},
	number = {11},
	year = {2019},
	month = {2019 Nov},
	pages = {979-988},
	abstract = {PR{\'e}CIS:: Neuroretinal rim minimum distance band (MDB) thickness is significantly lower in older subjects and African Americans compared with whites. It is similar in both sexes. PURPOSE: To evaluate the relationship between age, race, and sex with the neuroretinal rim using high-density spectral-domain optical coherence tomography optic nerve volume scans of normal eyes. METHODS: A total of 256 normal subjects underwent Spectralis spectral-domain optical coherence tomography optic nerve head volume scans. One eye was randomly selected and analyzed for each subject. Using custom-designed software, the neuroretinal rim MDB thickness was calculated from volume scans, and global and quadrant neuroretinal rim thickness values were determined. The MDB is a 3-dimensional neuroretinal rim band comprised of the shortest distance between the internal limiting membrane and the termination of the retinal pigment epithelium/Bruch{\textquoteright}s membrane complex. Multiple linear regression analysis was performed to determine the associations of age, race, and sex with neuroretinal rim MDB measurements. RESULTS: The population was 57\% female and 69\% white with a mean age of 58.4{\textpm}15.3 years. The mean MDB thickness in the normal population was 278.4{\textpm}47.5 {\textmu}m. For this normal population, MDB thickness decreased by 0.84 {\textmu}m annually (P\&lt;0.001). African Americans had thinner MDBs compared with whites (P=0.003). Males and females had similar MDB thickness values (P=0.349). CONCLUSION: Neuroretinal rim MDB thickness measurements decreased significantly with age. African Americans had thinner MDB neuroretinal rims than whites.},
	issn = {1536-481X},
	doi = {10.1097/IJG.0000000000001381},
	author = {Antar, Hussein and Tsikata, Edem and Ratanawongphaibul, Kitiya and Zhang, Jing and Shieh, Eric and Lee, Ramon and Freeman, Madeline and Papadogeorgou, Georgia and Simavli, Huseyin and Que, Christian and Verticchio Vercellin, Alice C and Khoueir, Ziad and de Boer, Johannes F and Chen, Teresa C}
}
