@article {1498257,
	title = {Reliability of Conjunctival Biopsy for Diagnosis of Ocular Mucous Membrane Pemphigoid: Redetermination of the Standard for Diagnosis and Outcomes of Previously Biopsy-Negative Patients},
	journal = {Ocul Immunol Inflamm},
	year = {2020},
	month = {2020 Mar 04},
	pages = {1-8},
	abstract = {: To demonstrate the reliability of conjunctival biopsy analyzed by direct immunofluorescence (DIF) and supplemented with avidin-biotin complex immunoperoxidase (ABC) in diagnosing oMMP, and report therapy response in biopsy-positive patients, particularly when previously biopsy-negative elsewhere.: Retrospective outcomes review of 136 consecutive patients after conjunctival biopsy for suspected oMMP.: Among 136 patients, 66\% were diagnosed with oMMP by DIF and 13\% via supplemental ABC immunoperoxidase. Sensitivity increased from 79.6\% with DIF to 95.6\% with supplemental ABC. Among 57 biopsy-positive patients, 77\% were in remission at 1-year follow-up and 88\% after 2 years. Of 34 previous biopsy-negative but now biopsy-positive patients with a 2-year follow-up, 91\% achieved remission, including all 16 diagnosed via DIF and ABC.: Conjunctival biopsy analyzed by histopathology and DIF supplemented by ABC has high reliability for diagnosing oMMP and is a useful tool to use before starting long-term immunomodulatory therapy in a patient with suspected oMMP.},
	issn = {1744-5078},
	doi = {10.1080/09273948.2020.1716988},
	author = {Anesi, Stephen D and Eggenschwiler, Laura and Ferrara, Mariantonia and Artornsombudh, Pichaporn and Walsh, Marisa and Foster, C Stephen}
}
