@article {1532359, title = {Galectins as Regulators of Corneal Inflammation}, journal = {Curr Opin Physiol}, volume = {19}, year = {2021}, month = {2021 Feb}, pages = {17-21}, abstract = {The cornea is a transparent avascular tissue on the anterior segment of the eye responsible for providing refractive power and forming a protective barrier against the external environment. Infectious and inflammatory conditions can compromise the structure of the cornea, leading to visual impairment and blindness. Galectins are a group of β-galactoside-binding proteins expressed by immune and non-immune cells that play pivotal roles in innate and adaptive immunity. In this brief review, we discuss how different members of this family of proteins affect both pro-inflammatory and anti-inflammatory responses in the cornea, particularly in the context of infection, transplantation and wound healing. We further describe recent research showing beneficial effects of galectin-targeted therapy in corneal diseases.}, issn = {2468-8673}, doi = {10.1016/j.cophys.2020.08.021}, author = {Arg{\"u}eso, Pablo} }