@article {1549032,
	title = {Analysis of Three-Dimensional Choroidal Volume with Enhanced Depth Imaging Findings in Patients with Recurrent Vogt-Koyanagi-Harada Disease},
	journal = {Curr Eye Res},
	volume = {46},
	number = {7},
	year = {2021},
	month = {2021 Jul},
	pages = {1010-1017},
	abstract = {Purpose: To demonstrate changes in three-dimensional choroidal volume with enhanced depth imaging optical coherence tomography (EDI-OCT) in patients with recurrent stage of Vogt-Koyanagi-Harada disease (VKH).Materials and Methods: This prospective comparative case series included 9 patients with recurrent VKH, 10 patients with quiet VKH, and 15 healthy controls after sample size was calculated. All VKH cases with recurrences underwent raster scanning with EDI-OCT at active and inactive stages of the disease.Results: All choroidal parameters in the active stage significantly reduced when the inflammation subsided: total choroidal volume (P =\&nbsp;.02), central choroidal volume (P =\&nbsp;.01), central choroidal thickness (P =\&nbsp;.03). The changes in central choroidal volume over the resolution phase were more pronounced than the changes in central choroidal thickness in 56\% of cases. Two cases presenting with only subclinical posterior segment recurrence had their choroidal parameters recovered after prompt treatment.Conclusions: In the recurrent stage of VKH, alteration in choroidal volume was evident by EDI-OCT even in an absence of anterior segment inflammation. Central choroidal volume may serve as a biomarker for detecting choroidal morphological change.},
	issn = {1460-2202},
	doi = {10.1080/02713683.2020.1849732},
	author = {Silpa-Archa, Sukhum and Ittharat, Worapon and Chotcomwongse, Peranut and Preble, Janine M and Foster, C Stephen}
}
