@article {1573100,
	title = {Topical cyclosporine a (0.05\%) treatment in dry eye patients: a comparison study of Sjogren{\textquoteright}s syndrome versus non-Sjogren{\textquoteright}s syndrome},
	journal = {Int Ophthalmol},
	volume = {41},
	number = {4},
	year = {2021},
	month = {2021 Apr},
	pages = {1479-1485},
	abstract = {PURPOSE: To evaluate the clinical effect of topical cyclosporine A (CsA) (0.05\%) on dry eye patients with Sjogren{\textquoteright}s syndrome (SS) and non-Sjogren{\textquoteright}s syndrome (NSS). METHOD: This retrospective comparative study includes the dry eye (DE) patients who were treated with topical CsA. DE patients were divided into two groups as follows: DE with Sjogren{\textquoteright}s syndrome (DE-SS) and DE with Non-Sjogren{\textquoteright}s syndrome (DE-NSS). Dry eye parameters were recorded at baseline and each visit. RESULTS: Schirmer{\textquoteright}s test 1 scores were 2.7 {\textpm} 0.5\&nbsp;mm at baseline and 3.5 {\textpm} 0.7\&nbsp;mm at 12th month in DE-SS, 2.9 {\textpm} 0.7\&nbsp;mm at baseline and 9.5 {\textpm} 0.7\&nbsp;mm in DE-NSS groups at 12th month. Mean ST score was higher in DE-NSS group than DE-SS group at sixth and 12th months of the treatment (both p = 0.001). Tear break-up time score showed a significant improvement in DE-NSS group, and it was lower in DE-NSS group than DE-SS group group at sixth and 12th months of the treatment (p = 0.044 and 0.027, respectively). Mean OSDI score was lower in DE-NSS group than DE-SS group at sixth and 12th months of the treatment (p = 0.030 and 0.032, respectively). CONCLUSION: Topical CsA seems to be more effective in the treatment of the DE-NSS.},
	issn = {1573-2630},
	doi = {10.1007/s10792-021-01708-1},
	author = {Cubuk, Mehmet Ozgur and Ucgul, Ahmet Yucel and Ozgur, Armagan and Ozulken, Kemal and Yuksel, Erdem}
}
