@article {1586144,
	title = {Ultra-widefield autofluorescence imaging findings in retinoschisis, rhegmatogenous retinal detachment and combined retinoschisis retinal detachment},
	journal = {Acta Ophthalmol},
	volume = {99},
	number = {2},
	year = {2021},
	month = {2021 Mar},
	pages = {195-200},
	abstract = {PURPOSE: Retinoschisis (RS), rhegmatogenous retinal detachment (RRD) and combined RS retinal detachment (RSRD) may resemble clinically and pose a diagnostic challenge. This study investigates the role of the fundus autofluorescence (AF) in differentiating RS, RRD and RSRD. METHODS: Fundus AF changes of 34 eyes diagnosed with RRD, 30 eyes with RS and 12 eyes with RSRD were retrospectively analysed. Ultra-widefield AF (UW-AF) image intensities obtained with the Optomap 200Tx were interpreted as hypo-, hyper- and isoautofluorescent or a mixed pattern with hypo- and hyperautofluorescence over and at the posterior margin (PM) of RRD, RS and RSRD. RESULTS: All RS eyes revealed isoautofluorescence over the area of RS, and nine eyes (30\%) showed hypoautofluorescent PM. Among RRD, acute (<=2\&nbsp;weeks) and chronic (\&gt;2\&nbsp;weeks) RRD demonstrated distinct AF characteristics. Sixty-two per cent of RRD eyes had acute RRD. From those, 16 eyes (76\%) demonstrated hypoautofluorescence over the detached area and 19 (90\%) eyes with hyperautofluorescent PM. Sixty-two per cent of chronic RRD eyes demonstrated isoautofluorecence over the detached area. Eight RSRD eyes (67\%) revealed hyperautofluorescence in the detached area. The positive predictive value (PPV) for hypoautofluorescence over the area of subretinal fluid (SRF) in RRD was 95\%. The PPV for hyperautofluorescence over the area of SRF in RSRD was 100\% and for isoautofluorescence for schitic area in RSRD and RS was 76\%. CONCLUSION: The UW-AF can be a useful non-invasive adjuvant tool to distinguish between RRD, RS and RSRD. Hypo- or hyperautofluorescence over the area of interest and hyperautofluorescent PM indicates the presence of SRF.},
	issn = {1755-3768},
	doi = {10.1111/aos.14521},
	author = {Navaratnam, Jesintha and Salvanos, Panagiotis and Vavvas, Demetrios G and Bragad{\'o}ttir, Ragnhei{\dh}ur}
}
