@article {1635621, title = {Effect of laser peripheral iridotomy on contrast sensitivity using Spaeth/Richman Contrast Sensitivity test}, journal = {Ther Adv Ophthalmol}, volume = {14}, year = {2022}, month = {2022 Jan-Dec}, pages = {25158414221078142}, abstract = {Background: Laser peripheral iridotomy (LPI) is the current standard of care for primary angle-closure glaucoma. The existing literature lacks evidence regarding the effects of LPI on contrast sensitivity (CS) after the procedure. Objective: This study evaluates central and peripheral CS in patients undergoing LPI using the computer-based, Spaeth/Richman Contrast Sensitivity (SPARCS) test. Methods: We performed a pilot, prospective, interventional cohort study including 30 patients of primary angle-closure suspect (PACS) or primary angle closure (PAC) in both eyes. LPI was performed after a detailed history and clinical examination using standard procedure in all eyes. Intraocular pressure (IOP) and CS testing using SPARCS was performed before, 2 weeks and 3 months after LPI. Results: Data analyses revealed female predominance (66.67\%, 20/30); the mean age of enrolled patients was 49.93 {\textpm} 10.43 years, and presenting acuity was 0.02 {\textpm} 0.06 (Log of Minimum Angle of Resolution [LogMAR]). The mean vertical cup-to-disc ratio (VCDR), mean deviation (MD in dB) and pattern standard deviation (PSD in dB) were 0.34 {\textpm} 0.09, -2.36 {\textpm} 1.72 and 2.34 {\textpm} 0.81, respectively. There was a statistically significant decrease between the pre- (15.17 {\textpm} 3.83 mmHg) and 2 weeks post-LPI (11.70 {\textpm} 1.53 mmHg) IOP (p \< 0.001). However, CS in the pre- (73.47 {\textpm} 9.88) and 3 months post-LPI (75.20 {\textpm} 11.98) SPARCS scores did not reveal any statistical difference. The group-wise analysis showed a similar trend between PAC and PACS patients. Conclusion: LPI does not affect central as well as peripheral CS assessment in patients with the primary angle-closure disease.}, issn = {2515-8414}, doi = {10.1177/25158414221078142}, author = {Ichhpujani, Parul and Thakur, Sahil and Singh, Tanu and Singh, Rohan Bir and Kumar, Suresh} }