@article {1635635,
	title = {Solving neurodegeneration: common mechanisms and strategies for new treatments},
	journal = {Mol Neurodegener},
	volume = {17},
	number = {1},
	year = {2022},
	month = {2022 Mar 21},
	pages = {23},
	abstract = {Across neurodegenerative diseases, common mechanisms may reveal novel therapeutic targets based on neuronal protection, repair, or regeneration, independent of etiology or site of disease pathology. To address these mechanisms and discuss emerging treatments, in April, 2021, Glaucoma Research Foundation, BrightFocus Foundation, and the Melza M. and Frank Theodore Barr Foundation collaborated to bring together key opinion leaders and experts in the field of neurodegenerative disease for a virtual meeting titled "Solving Neurodegeneration". This "think-tank" style meeting focused on uncovering common mechanistic roots of neurodegenerative disease and promising targets for new treatments, catalyzed by the goal of finding new treatments for glaucoma, the world{\textquoteright}s leading cause of irreversible blindness and the common interest of the three hosting foundations. Glaucoma, which causes vision loss through degeneration of the optic nerve, likely shares early cellular and molecular events with other neurodegenerative diseases of the central nervous system. Here we discuss major areas of mechanistic overlap between neurodegenerative diseases of the central nervous system: neuroinflammation, bioenergetics and metabolism, genetic contributions, and neurovascular interactions. We summarize important discussion points with emphasis on the research areas that are most innovative and promising in the treatment of neurodegeneration yet require further development. The research that is highlighted provides unique opportunities for collaboration that will lead to efforts in preventing neurodegeneration and ultimately vision loss.},
	issn = {1750-1326},
	doi = {10.1186/s13024-022-00524-0},
	author = {Wareham, Lauren K and Liddelow, Shane A and Temple, Sally and Benowitz, Larry I and Di Polo, Adriana and Wellington, Cheryl and Goldberg, Jeffrey L and He, Zhigang and Duan, Xin and Bu, Guojun and Davis, Albert A and Karthik Shekhar and Torre, Anna La and Chan, David C and Canto-Soler, M Valeria and Flanagan, John G and Subramanian, Preeti and Rossi, Sharyn and Brunner, Thomas and Bovenkamp, Diane E and Calkins, David J}
}
