@article {382216,
	title = {Visual outcomes in pediatric optic neuritis},
	journal = {Am J Ophthalmol},
	volume = {158},
	number = {3},
	year = {2014},
	month = {2014 Sep},
	pages = {503-7.e2},
	abstract = {PURPOSE: To describe the visual outcomes of a large cohort of pediatric patients presenting to a tertiary care pediatric hospital with first-episode optic neuritis. DESIGN: Retrospective, observational cohort study. METHODS: In a tertiary care pediatric hospital, patients with first-episode optic neuritis and at least 3 months of follow-up over a 10-year period were assessed and followed-up in the ophthalmology department. The main outcome measures were visual acuity at 3 months and 1 year of follow-up, with analysis of risk factors for poor visual outcomes and the time course of visual recovery. RESULTS: Of the 59 pediatric patients with first-episode optic neuritis, 46 had at least 3 months of follow-up and 36 had at least 1 year of follow-up. The mean age was 12.6 years old; 72\% were female, 41\% had bilateral involvement, 52\% had or developed an underlying diagnosis (39\% multiple sclerosis, 7\% acute disseminated encephalomyelitis, 7\% neuromyelitis optica), and 91\% received treatment (85\% steroids, 7\% multimodal). At 1 year, 81\% were at least 20/20 and 89\% were at least 20/40. A poor visual outcome at 1 year (\&lt;20/40) was associated with vision of \&lt;20/20 at 3 months (P = 0.041). Other clinical characteristics, including visual acuity at presentation, sex, bilateral involvement, optic nerve edema, and underlying diagnoses were not significantly associated with poor visual outcomes. CONCLUSIONS: In this cohort of pediatric patients with optic neuritis, the majority of patients regained normal visual acuity at 1 year, regardless of baseline clinical characteristics.},
	keywords = {Adolescent, Child, Child, Preschool, Disease Progression, Female, Follow-Up Studies, Forecasting, Humans, Male, Optic Neuritis, Retrospective Studies, Visual Acuity},
	issn = {1879-1891},
	doi = {10.1016/j.ajo.2014.05.036},
	author = {Wan, Michael J and Adebona, Olumuyiwa and Benson, Leslie A and Gorman, Mark P and Heidary, Gena}
}
