@article {742301,
	title = {Vascular Endothelial Cell Growth Factor A Acts via Platelet-Derived Growth Factor Receptor α To Promote Viability of Cells Enduring Hypoxia.},
	journal = {Mol Cell Biol},
	volume = {36},
	number = {18},
	year = {2016},
	month = {2016 Sep 15},
	pages = {2314-27},
	abstract = {Vascular endothelial cell growth factor A (VEGF) is a biologically and therapeutically important growth factor because it promotes angiogenesis in response to hypoxia, which underlies a wide variety of both physiological and pathological settings. We report here that both VEGF receptor 2 (VEGFR2)-positive and -negative cells depended on VEGF to endure hypoxia. VEGF enhanced the viability of platelet-derived growth factor receptor α (PDGFRα)-positive and VEGFR2-negative cells by enabling indirect activation of PDGFRα, thereby reducing the level of p53. We conclude that the breadth of VEGF{\textquoteright}s influence extends beyond VEGFR-positive cells and propose a plausible mechanistic explanation of this phenomenon.},
	issn = {1098-5549},
	doi = {10.1128/MCB.01019-15},
	author = {Pennock, Steven and Kim, Leo A and Kazlauskas, Andrius}
}
