@article {742306,
	title = {Resident corneal c-fms(+) macrophages and dendritic cells mediate early cellular infiltration in adenovirus keratitis.},
	journal = {Exp Eye Res},
	volume = {147},
	year = {2016},
	month = {2016 Jun},
	pages = {144-7},
	abstract = {The cornea contains a heterogeneous population of antigen-presenting cells with the capacity to contribute to immune responses. Adenovirus keratitis is a severe corneal infection with acute and chronic phases. The role of resident corneal antigen-presenting cells in adenovirus keratitis has not been studied. We utilized transgenic MaFIA mice in which c-fms expressing macrophages and dendritic cells can be induced to undergo apoptosis, in a mouse model of adenovirus keratitis. Clinical keratitis and recruitment of myeloperoxidase and CD45(+) cells were diminished in c-fms depleted, adenovirus infected mice, as compared to controls, consistent with a role for myeloid-lineage cells in adenovirus keratitis.},
	issn = {1096-0007},
	doi = {10.1016/j.exer.2016.05.016},
	author = {Ramke, Mirja and Zhou, Xiaohong and Materne, Emma Caroline and Rajaiya, Jaya and Chodosh, James}
}
