@article {836881,
	title = {Clear-Cell (Reticulated) Transformation of Eyelid Eccrine Sweat Glands.},
	journal = {Ophthal Plast Reconstr Surg},
	year = {2016},
	month = {2016 Jul 21},
	abstract = {A 24-year-old man with a painful, recurrent left upper eyelid nodule underwent an excision. Histopathologic evaluation disclosed a granulomatous process, most likely in response to a ruptured epidermoid cyst. In the vicinity of the nodule were multiple eccrine sweat glands displaying a curious clear-cell appearance in the adlumenal cells, the first example of such a phenomenon in the eyelids. Alcian blue, periodic acid Schiff, and documented staining failed to disclose, respectively, any cytoplasmic mucosubstances, glycogen accumulation, or lipid in the adlumenal secretory cells. Cytokeratin 7 immunostained the adlumenal cells of the eccrine secretory coil, while cytokeratin 5/6 stained the ablumenal myoepithelial and ductular cells. Gross cystic disease fluid protein 15, normally demonstrable in the eccrine secretory cells, was not detectable. Clear-cell transformation should not be confused with syringoma of the lower eyelids, in which glycogen is responsible for the ablumenal clear-cell change.},
	issn = {1537-2677},
	doi = {10.1097/IOP.0000000000000761},
	author = {Jakobiec, Frederick A and Stagner, Anna M and Lee, Nahyoung Grace}
}
