%0 Journal Article %J Ocul Immunol Inflamm %D 2018 %T The Challenge of Pediatric Uveitis: Tertiary Referral Center Experience in the United States %A Ferrara, Mariantonia %A Eggenschwiler, Laura %A Stephenson, Andrew %A Montieth, Alyssa %A Nakhoul, Nakhoul %A Araùjo-Miranda, Rafael %A Foster, C Stephen %X PURPOSE: To describe the distribution, clinical findings, visual outcomes, treatment, and complications of children with uveitis at a tertiary referral ophthalmic center. METHODS: Retrospective cohort study. We reviewed the medical records of all patients ≤16 years with uveitis referred to Massachusetts Eye Research and Surgery Institution from March 2005 to July 2016. RESULTS: Of 286 included children, 62.24% were female. Mean age of onset was 8.4 years. The uveitis was mainly anterior (61.9%), recurrent (68.53%), bilateral (81.82%), and noninfectious (96.5%). Idiopathic cases accounted for 51.4%. The most frequent systemic association was juvenile idiopathic arthritis (34.96%). The majority of patients (78.32%) experienced complications. All patients, except one, needed systemic therapy. CONCLUSION: Pediatric uveitis is challenging to diagnose and manage, with frequent and potentially severe complications. Most cases were bilateral, recurrent, and idiopathic. Prompt referral to uveitis-specialized centers and an appropriate systemic therapy are mandatory for good visual outcomes. %B Ocul Immunol Inflamm %P 1-8 %8 2018 Jan 15 %G eng %1 http://www.ncbi.nlm.nih.gov/pubmed/29333911?dopt=Abstract %R 10.1080/09273948.2017.1420202