%0 Journal Article %J J Neuroophthalmol %D 2018 %T Tacrolimus Optic Neuropathy %A Rasool, Nailyn %A Boudreault, Katherine %A Lessell, Simmons %A Prasad, Sashank %A Cestari, Dean M %X BACKGROUND: Tacrolimus (FK506, Prograf) is a potent immunosuppressant, which inhibits cytokine synthesis and blocks T-cell development. Optic neuropathy from tacrolimus toxicity is very uncommon but, when present, can result in severe vision loss. METHODS: Case series and review of the literature. RESULTS: We present 3 patients with tacrolimus optic neuropathy after bone marrow transplantation complicated by graft-vs-host disease and demonstrate the differing clinical and radiologic presentation of this presumed toxic optic neuropathy. CONCLUSIONS: Tacrolimus optic neuropathy can manifest in a multitude of clinical presentations and can have devastating visual consequences. %B J Neuroophthalmol %V 38 %P 160-166 %8 2018 Jun %G eng %N 2 %1 http://www.ncbi.nlm.nih.gov/pubmed/29420328?dopt=Abstract %R 10.1097/WNO.0000000000000635