%0 Journal Article %J Ocul Immunol Inflamm %D 2020 %T Combination of Intravenous Methotrexate and Methylprednisolone Therapy in the Treatment of Severe Ocular Inflammatory Diseases %A Maleki, Arash %A Ueberroth, Jordan A %A Walsh, Marisa %A Foster, Frances %A Chang, Peter Y %A Anesi, Stephen D %A Foster, Charles Stephen %X : To evaluate the efficacy of intravenous methotrexate and methylprednisolone in severe, sight-threatening ocular inflammatory conditions.: This was a retrospective observational case series. Patients who had received intravenous methotrexate for ocular inflammation with at least 24 months of follow-up were included in the study.: Ten patients (20 eyes) were included in this study. Mean age of the patients was 47.2 ± 17.7 (range:19-74). At 1-month follow-up visit, nine patients showed improvement and one patient failed treatment. At 12-month follow-up visit, all patients were in remission. Two patients were only on intravenous methotrexate infusions. At twenty-four-month follow-up visit, only one patient, in remission, was on intravenous methotrexate therapy. Leukopenia was the only adverse effect observed.: Intravenous methotrexate and methylprednisolone infusions can be an effective method of treatment in patients with severe, sight-threatening ocular inflammatory conditions. %B Ocul Immunol Inflamm %P 1-5 %8 2020 May 14 %G eng %1 http://www.ncbi.nlm.nih.gov/pubmed/32406782?dopt=Abstract %R 10.1080/09273948.2020.1746356