%0 Journal Article %J J Neuroophthalmol %D 2016 %T An Atypical Case of Lymphocytic Panhypophysitis in a Pregnant Woman. %A Davies, Emma C %A Jakobiec, Frederick A %A Stagner, Anna M %A Rizzo, Joseph F %X

We describe a case of lymphocytic panhypophysitis (LPH) in a 30-year-old woman presenting with throbbing headaches and vision changes during her third trimester. LPH is the rarest subclassification of lymphocytic hypophysitis; it is typically found in males and has not previously been associated with pregnancy. Anterior and posterior pituitary deficits together with headaches should raise a high degree of suspicion regarding the possibility of LPH. The atypical magnetic resonance imaging finding of a heterogeneous pituitary mass additionally raised concern about pituitary apoplexy. Tissue from a transsphenoidal biopsy permitted diagnosis of lymphocytic hypophysitis. There was infiltration of the pituitary gland by small B and T lymphocytes. Resolution of the visual symptoms occurred after the biopsy and treatment with intravenous steroids.

%B J Neuroophthalmol %V 36 %P 313-6 %8 2016 Sep %G eng %N 3 %1 http://www.ncbi.nlm.nih.gov/pubmed/27008424?dopt=Abstract %R 10.1097/WNO.0000000000000362