New research findings may lead to development of new therapies to delay or prevent the development of diabetic eye disease.
Boston, Mass. — Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease (known as diabetic retinopathy). Their findings,
Mass. Eye and Ear researchers describe, for the first time, an association between a defective myogenic response of blood vessels in the retina and early, accelerated development of retinopathy in patients with type 1 diabetes. The findings may lead to the development of targeted therapies to delay or prevent the development of diabetic retinopathy in this population.