5th Biennial International Symposium on AMD

Today, age-related macular degeneration (AMD) remains a leading cause of blindness in developed countries—affecting more than 15 million in the United States alone.

This October, vision scientists and researchers from related fields will come together to discuss the latest topics in AMD research, ranging from novel biomarkers and vascular pathogenesis to inflammation. The goal of this symposium is to propel innovative AMD research that will ultimately eradicate this blinding disease

The event is hosted by the Harvard Ophthalmology AMD Center of Excellence and presented in partnership with the 3rd Biennial International Symposium on Ocular Regeneration.

Event Highlights

Thursday, October 11
6-8pm

Welcome Reception  (included in registration)

Friday, October 12
7am-5:15pm

Scientific lectures
Friedman Lecture: presented by Francois Delori, PhD
Gala Dinner at the Boston Museum of Science (registration fees apply)

Saturday, October 13
7am-3:40pm
Scientific lectures

Register for the AMD Symposium (2 Days):

Attendee Register by May 31 Register after May 31
Harvard Ophthalmology Faculty $200 $250
Academic $275 $325
Industry or corporate $500 $650
Trainee Complimentary (Thanks to support from the NEI/NIH) Complimentary (thanks to support from the NEI/NIH)

Register for AMD and Ocular Regeneration Symposia (3 Days):

Attendee Register by May 31 Register after May 31
Academic $350 $400
Industry or corporate $750 $900

 

Members of the Organizing Committee include: Patricia A. D’Amore, PhD, MBA, Co-chair; Deeba Husain, MD, Co-chair; Ivana K. Kim, MD, Co-chair; and Joan W. Miller, MD, Ex-officio.

Up to 10 Travel Awards will be given, thanks to support from an NEI/NIH conference grant. Selected winners will also present a poster during the symposium. 

Submissions are currently under review. Travel award winners will be contacted before September 1, 2018. 

 

Email erin_porter@meei.harvard.edu to learn about exhibit and sponsorship opportunities. This year’s sponsors include:

Platinum

Broadhurst Foundation

Gold

Genentech
Regeneron

Silver

Biogen

Bronze

Heidelberg Engineering
Macular Degenenation Foundation

Thursday, October 11

Welcome Reception
6:00-8:00pm
Mass Eye and Ear
243 Charles Street
7th Floor Cafeteria

Friday, October 12

Welcome Breakfast and Registration
7:00-8:00am
Starr Center
185 Cambridge Street, 2nd Floor

8:00am

Welcome

Joan Miller, MD
Chair, Harvard Ophthalmology; Chief of Ophthalmology, Mass. Eye and Ear and Mass General Hospital

8:05am

Opening address

Anthony P. Adamis, MD
Global Head of Ophthalmology, Immunology and Infectious Diseases, Genentech/Roche

Biomarkers
Moderator: Deeba Husain
Associate Professor of Ophthalmology
Harvard Medical School (HMS)

8:30am

Biomarkers of AMD: Dark adaptation, function and imaging

Emily Chew, MD
Director, Division of Epidemiology and Clinical Applications, National Eye Institute (NEI), National Institutes of Health (NIH)

8:55am

The utility of metabolomics in an integrative omics era

Jessica Lasky-Su, ScD
Associate Professor of Medicine, Brigham and Women's Hospital

9:20am

Targeting of miR-33 in age-related macular degeneration

Anders M. Naar, PhD
Assistant Cell Biologist, Professor of Cell Biology, Center for Cancer Research, Mass General Hospital

9:45am

Discussion

Break (10:25am)

 

Vascular
Moderator: Demetrios Vavvas, MD, PhD
Associate Professor of Ophthalmology, HMS

10:45am

Deletion of endothelial TGF-β signaling promotes choroidal neovascularization

Barbra Braunger, MD, PhD,
Group Leader, University of Regensburg, Germany

11:10am

Identification novel angiogenesis regulating genes by genome association studies in mice

Robert D'Amato, MD, PhD
Professor of Ophthalmology, HMS

11:35am

New insights into MacTel2 and type 3 neovascularization from optical coherence tomography angiography imaging

Richard F. Spaide, MD
Retina Specialist, Vitreous Retina Macula Consultant Of New York; Clinical Assistant Professor, New York University

12:00pm

Discussion

Lunch (12:40pm)

 

Inflammation
Moderator: Kip Connor
Assistant Professor of Ophthalmology, HMS

1:40pm

Immunotherapy regulating immune responses through metabolic sensing

Andrew Dick MD
Professor of Ophthalmology, University of Bristol

2:05pm

Rethinking nuclear receptors as therapeutic targets for AMD

Goldis Malek, PhD
Associate Professor, Departments of Ophthalmology and Pathology, Duke Eye Center

2:30pm

Intracellular complement activation in the retinal pigment epithelium

Aparna Lakkaraju, PhD
Associate Professor, Department of Ophthalmology, University of California, San Francisco

2:55pm Discussion

Break (3:35pm)

4:00pm

Introduction to Friedman Lecture

Evangelos Gragoudas, MD
Charles Edward Whitten Professor of Ophthalmology, HMS

4:10pm

Introduction to speaker

Joan Miller, MD

4:15pm

Friedman Lecture:
Fundus autofluorescence

Francois Delori, PhD
Professor of Ophthalmology, HMS

Gala Dinner
Boston Museum of Science
6:00-10:00pm
(registration required)

Saturday, October 13

Welcome Breakfast
7:00-8:00am

8:00am

Welcome back

Ivana Kim, MD
Associate Professor of Ophthalmology, HMS, Mass. Eye and Ear

8:10am

Trainee Rapid Fire Session

Selected Travel Award Winners (TBD)

Break (9:25am)

 

Epigenetics
Moderator: Margaret DeAngelis, PhD
Professor of Ophthalmology/Visual Sciences, University of Utah

9:45am

Epigenetics of aging and cancer: A nutritional perspective

Trygve Tollefsbol, PhD, DO
Professor of Biology, Senior Scientist, University of Alabama at Birmingham

10:10am

Defining the functional epigenome

Myles Brown, MD
Professor of Medicine, Dana-Farber Cancer Institute, HMS

10:35am

Transcriptomic analysis of at single-cell resolution in neurodegeneration

Li-Huei Tsai, PhD
Picower Institute Director, Principal Investigator, Massachusetts Institute of Technology

11:00am

Discussion

Lunch (11:40am)

 

Mitochondria
Moderator: Scott W. Cousins, MD
Robert Machemer, MD Professor of Ophthalmology, Professor in Immunology, Vice-chair, Research, Department, Duke University

12:40pm 

Mitochondrial dysfunction in the retinal Pigment epithelium promotes AMD pathology

Deborah Ferrington, PhD
Professor, Department of Ophthalmology and Visual Neurosciences, University of Minnesota

1:05pm 

Role of mitochondrial oxidative stress in cerebromicrovascular aging

Zoltan Ungvari, MD, PhD
Associate Professor of Geriatric Medicine, Donald W. Reynolds Chair of Aging Research, University of Oklahoma Health

1:30pm 

Metabolic control of RPE phenotype

Magali Saint-Geniez, PhD
Assistant Professor of Ophthalmology, HMS

1:55pm

Discussion

Break (2:35pm)

3:00pm

Closing Remarks

Patricia D'Amore, PhD, MBA
Charles L. Schepens Professor of Ophthalmology and Pathology, Vice Chair of Basic and Translational Research, HMS