Research

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New technique may prevent graft rejection in high-risk corneal transplant patients

May 1, 2017

Treating donor tissue with a special cocktail of molecules improves outcomes and promotes survival of high-risk corneal transplants

Boston, Mass. — Treating donor corneas with a cocktail of molecules prior to transplanting to a host may improve survival of grafts and, thus, outcomes in high-risk corneal transplant patients, according to a new study led by researchers at Massachusetts Eye and Ear. The findings, ...

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Researchers identify mechanism of retina damage following chemical eye burns

Researchers identify mechanism of retina damage following chemical eye burns

April 13, 2017

Findings may lead to the development of therapies to prevent damage to the retina, the light-sensitive tissue at the back of the eye.

Boston, Mass. — Chemical eye burns caused by alkali agents not only injure the front of the eye — the cornea, where the contact takes place —  but also cause widespread damage to the light-sensitive tissue at the back of the eye (the retina) as well, often leading to optic nerve damage and glaucoma. In a report...

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Researchers identify new target for abnormal blood vessel growth in the eyes

April 11, 2017

Regulating transcription factor RUNX1 using small molecule drugs a promising novel therapy for diseases of the retina, including advanced diabetic eye disease.

Boston, Mass.— A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced diabetic eye disease (proliferative diabetic retinopathy).... Read more about Researchers identify new target for abnormal blood vessel growth in the eyes

Brain "rewires" itself to enhance other senses in blind people

Brain "rewires" itself to enhance other senses in blind people

March 22, 2017

Boston, Mass. — The brains of those who are born blind make new connections in the absence of visual information, resulting in enhanced, compensatory abilities such as a heightened sense of hearing, smell and touch, as well as cognitive functions (such as memory and language) according to a new study led by Massachusetts Eye and Ear researchers. The report, published online today...

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ARVO 2013

January 1, 2014

May 5-9, 2013 – Seattle, WA

 At this year’s meeting, held in Seattle, Washington from May 5–9, faculty, trainees and research fellows authored 239 abstracts, including 44 papers and 195 research posters representing the investigative work of nearly 230 individuals, including 90+ faculty, 20 clinical fellows, 19 residents, and over 100 research fellows. ARVO Travel Grants were awarded to nine department members, while a significant number of Harvard Ophthalmology faculty and alumni received ARVO awards honors....

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arvo 2016

ARVO 2016

April 28, 2016

From May 1st to May 5th, more than 11,000 people attended the Association for Research in Vision and Ophthalmology (ARVO) 2016 Annual Meeting in Seattle, WA. Eye and vision researchers from more than 75 countries presented their current research, discussed emerging technologies, and strategized ways to overcome the current challenges facing ophthalmology and vision science. Harvard Ophthalmology was well-represented at the meeting, and faculty and trainees contributed 247 posters and presentations this year.

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ONL Therapeutics Announces Formation of Scientific Advisory Board

ONL Therapeutics Announces Formation of Scientific Advisory Board

October 14, 2015

ONL Therapeutics, Inc., a biopharmaceutical company developing novel therapies for preserving sight in a range of retinal diseases, has announced that Joan W. Miller, MD, Chair of the Department of Ophthalmology, Harvard Medical School and Chief of Ophthalmology at Massachusetts Eye and Ear and Massachusetts General Hospital, is one of five of the world’s premier retinal disease thought leaders who will serve on its newly formed scientific advisory board (SAB). The goal of...

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Jason Comander and Leo Kim discuss vision research with members of Congress

Jason Comander and Leo Kim discuss vision research with members of Congress

October 13, 2015

On October 7th and 8th, Jason Comander, MD, PhD, and Leo Kim, MD, PhD, participated in the Alliance for Eye and Vision Research (AEVR) Emerging Vision Scientists Program. This program allows scientists to meet with members of Congress to discuss the importance of vision research in the continuing fight to prevent blindness. 

Dr...

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Targeting the Immune System to Prevent Vision Loss

Targeting the Immune System to Prevent Vision Loss

July 22, 2015

Vision researchers at Mass. Eye and Ear/Harvard Medical School (HMS) Department of Ophthalmology have taken a first step in solving a vexing problem: how to preserve photoreceptor cells and avoid irreversible vision loss in patients following retinal detachment. 

Degeneration of photoreceptors, the major light-sensing cells in the eye, is a primary cause of vision loss worldwide. Identifying the underlying causes surrounding photoreceptor cell death is paramount in order to develop new treatment strategies to prevent their loss. Retinal detachment and subsequent degeneration of...

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Researchers Resurrect Ancient Viruses in Hopes of Improving Gene Therapy

Researchers Resurrect Ancient Viruses in Hopes of Improving Gene Therapy

July 30, 2015

Boston, MA Researchers at Massachusetts Eye and Ear and Schepens Eye Research Institute have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina. This discovery, published July 30 in Cell Reports, could potentially be used to design gene therapies that are not only safer and more potent than therapies currently...

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