September 4, 2019
The Massachusetts Lions Eye Research Fund awarded $175,000 in grants to support four research projects at Schepens Eye Research Institute of Mass Eye and Ear.
- Corinna Bauer, PhD, will implement multi-modal neuroimaging methods to help uncover the potential mechanisms underlying increased visual processing delays observed in children with perinatal brain injury.
- Tatjana Jakobs, MD, and Meredith Gregory-Ksander, PhD, are studying the role of microglia--- the resident immune cells of the eye, and optic nerve--- and their potential to act as glaucoma therapy.
- Eric Ng, PhD, aims to identify potent inhibitors for endothelial-to-mesenchymal transition (EndoMT) and to determine the therapeutic potential of targeting EndoMT for choroidal neovacularization associated with wet AMD that is resistant to anti-VEGF treatment.
- Magali Saint-Geniez, PhD, will investigate the mechanism underlying the distinctive centrifugal progression of RPE atrophy in advanced dry AMD – specifically how diseased RPE spread damage to neighboring cells by affecting their metabolic state and how to target this new phenomenon for therapeutic application.