Isaac Bleicher, MD

Isaac Bleicher, MD

Chief Resident (2023-2024)
Instructor in Ophthalmology
Director, Mass Eye and Ear Eye Trauma Service
Isaac Bleicher

 

Dr. Isaac Bleicher serves as the Coordinator and Director of the Eye Trauma Service at Massachusetts Eye and Ear and the Brigham and Women’s Hospital. In addition, Dr. Bleicher serves as a mentor, teacher, and peer resource to Harvard Ophthalmology’s residency program.

He earned his MD from Duke University School of Medicine, where he was inducted into the Alpha Omega Alpha Honor Society and received the Deans Award and Senior Merit Scholarship. He assisted with community eye screenings at Special Olympics events and local health fairs.

As a medical student, Dr. Bleicher performed research in optical coherence tomography, specifically developing, programming, and testing novel data visualizations for 3D display of microscope-integrated optical coherence tomography (MIOCT) data to guide ophthalmic surgery in real time. He operated, troubleshooted, and improved a research MIOCT system for human surgery. During residency, he worked to subclassify open globe injuries by outcome, creating the only quantitative work supporting current initiatives to review the categorization of these injuries. His most current research focuses on identifying the structural and functional correlates to genetic risk factors in central serous chorioretinopathy (CSCR) by conducting quantitative analysis of OCT data. He aims to show how choroidal structural and vascular flow varies based on identified genetic risk factors. Additionally, his interest in technology development has led to using wide-field OCT angiography to analyze choroidal vascular patterns and correlating these findings to measures of retinal disease in diabetic retinopathy, as well as analyzing a cohort of patients with Wagner’s syndrome and suggesting a pathophysiology of this syndrome’s perivascular retinal atrophy. He also uses artificial intelligence to differentiate CSCR and age-related macular degeneration by automatic analysis of OCT images.

Dr. Bleicher’s work has been published in publications such as OphthalmologyJournal of PediatricsTranslational Vision Science and TechnologyMedical Science Education, and Graefe’s Archive for Clinical and Experimental Ophthalmology. He has presented his work at Association for Research in Vision and Ophthalmology Annual Meeting, Alpha Omega Alpha Medical Student Research Day, American Society of Retina Surgeons, XXXIst Meeting of the Club Jules Gonin, and the Consortium of Longitudinal Integrated Clerkships in Singapore. He holds a US patent for “Systems and Methods for Providing Surface Contrast in Rendering of Three-Dimensional Images for Micro-Surgical Applications.”

 

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