Angiofibroma of the Eyelid: A Rare Clinical and Histologic Variant

Citation:

Charles NC, Jakobiec FA, Ma L, Belinsky I. Angiofibroma of the Eyelid: A Rare Clinical and Histologic Variant. Ophthalmic Plast Reconstr Surg 2019;35(4):e199-e102.

Date Published:

2019 Jul/Aug

Abstract:

A flesh-colored, supraciliary lesion of the left upper eyelid in a 47-year-old man was excised for cosmetic reasons. Histopathology and immunohistochemistry demonstrated CD34-positive benign spindle cells, factor XIIIa-positive dendritic cells, and CD163-positive histiocytes, all dispersed within a diffuse collagenous background. Prominent loose perivascular cuffs of fibroblastic cells and collagen surrounded small blood vessels. Interpreted as an angiofibroma, the histopathology bore resemblance to that of a single previously-reported forearm lesion termed a "dermal fibroma with a distinctive perivascular cell arrangement." The lesion represents the first eyelid example of an unusual variant of angiofibroma.

Last updated on 07/31/2019