Age-related Macular Degeneration

Demetrios Vavvas's headshot

New study shows strong interaction between genetics and nutritional supplement treatment on progression to neovascular age-related macular degeneration (AMD)

January 18, 2018

In a study published on January 8, 2018 in the Proceedings of the National Academy of Sciences (PNAS), Demetrios G. Vavvas, MD, PhD, Associate Professor of Ophthalmology at Harvard Medical School and Incumbent of the Monte J. Wallace Ophthalmology Chair in Retina at Mass. Eye and Ear, as well as investigators from University of Toronto and Stanford University, addressed a controversial topic in the field of...

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The back of the eye in a patient with AMD, showing multiple large drusen deposits and pigment changes

Researchers identify potential biomarkers of age-related macular degeneration

September 12, 2017

Findings may lead to earlier diagnoses and better prognostic information for patients — and, potentially, new pharmaceutical targets for AMD treatment.

Boston, Mass. — Patients with any stage of age-related macular degeneration (AMD) carry signs of the disease in their blood that may be found through special laboratory tests, according to a new study led by AMD researchers based at Massachusetts Eye and Ear. The study, ...

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Researchers identify key compounds to resolve abnormal vascular growth in age-related macular degeneration

August 22, 2017

Findings may have significant therapeutic implications for AMD, the most common cause of elderly blindness in the developed world

kip connor at a microscope

Boston, Mass. — A compound of specific bioactive products from a major family of enzymes reduced the severity of age-related...

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Symposium on AMD Gala Dinner at the Liberty Hotel, Boston

AMD Symposium Facilitates Open Dialogue on Innovative Research

November 3, 2016

At the fourth Biennial International Symposium on AMD, held October 21-22, 2016 in Boston, more than 200 clinicians, researchers, trainees, and industry representatives discussed current AMD topics and the challenges that lay ahead. One of the central themes of this year’s symposium was the need for a more precise stratification of the disease.

Organized byHarvard Ophthalmology AMD Center of Excellence Co-directors— ...

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Patients with High-Risk Macular Degeneration Show Improvement with High-Dose Statin Treatment

Patients with High-Risk Macular Degeneration Show Improvement with High-Dose Statin Treatment

February 4, 2016

A phase I/II clinical trial at Massachusetts Eye and Ear found that some patients taking high doses of atorvastatin (cholesterol-lowering medication) had complete resolution of lipid deposits in the dry form of age-related macular degeneration (AMD). AMD is the leading cause of blindness in the developed world, and though effective treatments are available for the wet AMD, they are currently lacking for the more-prevalent dry form.

...

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Eyes on the Complement System at the Third International Biennial Symposium on AMD 

October 27, 2014

Drawing nearly 250 clinicians, researchers, trainees, and industry representatives from around the world, the Third International Biennial Symposium on AMD, which was held October 24–25, 2014 and co-chaired by Chief and Chair of Ophthalmology, Joan Miller, MD, FARVO, and AMD Center of Excellence co-directors Patricia D’Amore, PhD, MBA, FARVO and Ivana Kim, MD, had special significance because it followed the 2014 António Champalimaud Vision Award, which recognized the development of antiangiogenic therapies for AMD and other retinal diseases. Five members of the HMS Department of...

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200+ Scientists and Clinicians Brainstorm at the 2nd Biennial International Symposium on Age-related Macular Degeneration

September 22, 2012

On September 21-22, 2012, Harvard Ophthalmology hosted its 2nd Biennial International Symposium on age-related macular degeneration (AMD), which spurred lively discussion and debate among more than 200 clinicians, researchers, and trainees in attendance. A diverse and distinguished group of AMD experts from around the world engaged in stimulating and open-ended panel discussions on a wide array of AMD topics that included RPE/Bruch’s membrane/choriocapillaris, infl ammation, lipids/cardiovascular...

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