Research

Novel Cell Atlas for Multiple Human Tissues Reveals Discoveries Underlying Complex Diseases

June 13, 2022

Scientists from the Broad Institute of Massachusetts Institute of Technology and Harvard have developed a first-of-its-kind cross-tissue cell atlas, and in collaboration with a team of Mass Eye and Ear researchers led by Ayellet V. Segrè, PhD, MSc, Assistant Professor of Ophthalmology at Harvard Medical School, have uncovered new clues for specific cell types and genes involved in complex diseases.... Read more about Novel Cell Atlas for Multiple Human Tissues Reveals Discoveries Underlying Complex Diseases

Joseph Arboleda-Velasquez, MD, PhD, Awarded $500,000 in Funding to Support Alzheimer's Research

February 8, 2022

Dr. Joe ArboledaJoseph Arboleda-Velasquez, MD, PhD, Assistant Professor of Ophthalmology at Harvard Medical School (HMS) and Assistant Scientist at Schepens Eye Research Institute of Mass Eye and Ear, is a 2022 recipient of the Edward N. & Della L. Thome Memorial Foundation Awards Program in Alzheimer's Disease Drug Discovery Research.... Read more about Joseph Arboleda-Velasquez, MD, PhD, Awarded $500,000 in Funding to Support Alzheimer's Research

Joseph F. Arboleda-Velásquez, MD, PhD, Receives $4 Million Research Gift

September 29, 2020

Dr. Joseph F. Arboleda-Velásquez in his laboratory

Joseph F. Arboleda-Velasquez, MD, PhD, an Assistant Professor of Ophthalmology at Harvard Medical School and assistant scientist at Mass Eye and Ear who studies small vessel disease in the brain and the eye, has been awarded a five-year, $4 million gift from Good Ventures to spur his lab’s groundbreaking work into Alzheimer’s disease genetic resistance.... Read more about Joseph F. Arboleda-Velásquez, MD, PhD, Receives $4 Million Research Gift

Researchers Uncover Mechanism for How Common Gene Therapy Vectors Enter Cells

January 24, 2020

Luk Vandenberghe

Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types—the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors–or vehicles—that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.... Read more about Researchers Uncover Mechanism for How Common Gene Therapy Vectors Enter Cells