Bilateral Upper and Lower Eyelid Margin Swelling and Madarosis due to Lymphoma

Citation:

Nguyen HV, Jakobiec FA, Zakka FR, Yoon MK. Bilateral Upper and Lower Eyelid Margin Swelling and Madarosis due to Lymphoma. Surv Ophthalmol 2017;

Date Published:

2017 Oct 03

Abstract:

Over a 2 year period a 32-year-old woman developed swellings of all 4 eyelid margins accompanied by complete loss of eyelashes. An inflammatory dermatologic condition was considered the most likely cause. A full thickness right lower eyelid biopsy revealed a multinodular lymphoid tumor at the eyelid margin which immunophenotypically and genetically was diagnosed as an extranodal marginal zone lymphoma. The mode of presentation of the disease was considered to be most unusual, as was its B cell lineage, since the majority of primary cutaneous lymphomas are of T-cell origin. Systemic workup demonstrated bilateral involvement of the external auditory canals.

Last updated on 10/24/2017