Glaucoma is an optic neuropathy that is characterized by the progressive degeneration of the optic nerve, leading to visual impairment. Glaucoma is the main cause of irreversible blindness worldwide, but typically remains asymptomatic until very severe. Open-angle glaucoma comprises the majority of cases in the United States and western Europe, of which, primary open-angle glaucoma (POAG) is the most common type. By contrast, in China and other Asian countries, angle-closure glaucoma is highly prevalent. These two types of glaucoma are characterized based on the anatomic configuration of the aqueous humour outflow pathway. The pathophysiology of POAG is not well understood, but it is an optic neuropathy that is thought to be associated with intraocular pressure (IOP)-related damage to the optic nerve head and resultant loss of retinal ganglion cells (RGCs). POAG is generally diagnosed during routine eye examination, which includes fundoscopic evaluation and visual field assessment (using perimetry). An increase in IOP, measured by tonometry, is not essential for diagnosis. Management of POAG includes topical drug therapies and surgery to reduce IOP, although new therapies targeting neuroprotection of RGCs and axonal regeneration are under development.
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Primary open-angle glaucoma. Nat Rev Dis Primers 2016;2:16067.Abstract
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Microcatheter-assisted trabeculotomy versus rigid probe trabeculotomy in childhood glaucoma. Br J Ophthalmol 2016;100(9):1257-62.Abstract
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Novel Insights Into the Immunoregulatory Function and Localization of Dendritic Cells. Cornea 2016;35 Suppl 1:S49-S54.Abstract
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Human Corneal Fibroblast Pattern Evolution and Matrix Synthesis on Mechanically Biased Substrates. Tissue Eng Part A 2016;22(19-20):1204-1217.Abstract
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Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications. Am J Physiol Heart Circ Physiol 2016;311(3):H738-49.Abstract
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Goblet cells of the conjunctiva: A review of recent findings. Prog Retin Eye Res 2016;54:49-63.Abstract
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Bioptic Telescope Use and Driving Patterns of Drivers with Age-Related Macular Degeneration. Transl Vis Sci Technol 2016;5(5):5.Abstract
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Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium. PLoS Genet 2016;12(9):e1006186.Abstract
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Electrical Stimulation as a Means for Improving Vision. Am J Pathol 2016;186(11):2783-2797.Abstract
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IGF-1 in retinopathy of prematurity, a CNS neurovascular disease. Early Hum Dev 2016;102:13-19.Abstract
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Assessing Resident Cataract Surgery Outcomes Using Medicare Physician Quality Reporting System Measures. J Surg Educ 2016;73(5):774-9.Abstract
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